Intravaginal Suppository Probiotic May Reduce Rate of Recurrent Urinary Tract Infections

The results of a new study suggest that probiotic may reduce the rate of recurrent urinary tract infections in women prone to these infections.

There is a theory that a depletion of vaginal lactobacilli, a type of bacteria, is associated with urinary tract infection risk, which suggests that replenishing this bacteria may be beneficial.

A double blind placebo controlled trial to investigate this theory was conducted.  In the study, young women with a history of recurrent urinary tract infections received antibiotics for acute urinary tract infections. They were then randomized to receive either a Lactobacillus crispatus intravaginal suppository probiotic, called LACTIN-V, or a placebo for five days, then once a week for 10 weeks. Fifty women out of the 100 women who participated in the study received LACTIN-V, and 50 received the placebo.  Seven of the women who received LACTIN-V had at least one urinary tract infection, compared to 13 in the placebo group.

Study author Ann Stapleton, MD, of the University of Washington in Seattle said “Larger efficacy trials of this novel preventive method for recurrent urinary tract infections are warranted to determine if use of vaginal Lactobacillus could replace long term antimicrobial preventive treatments.”

Urinary tract infections are more comment in women which frequently recurs affecting 2 to 3 percent of all women.  In United States alone, cost to treat these infections is estimated at $2.5 billion in year 2000.

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