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No Relationship Found Between Weight Changes and LUTS


Even though obesity has been related to lower urinary tract symptoms (LUTS) in aging men, new findings from researchers at the Mayo Clinic College of Medicine in Rochester, Minnesota suggest that modest weight loss may not prevent the onset or progression of LUTS among these men.  Also, no relationship was found between weight gain and the development or progression of LUTS.

The research team analyzed data from 1,674 white men participating in the Olmstead County Study (OCS) of Urinary Symptoms and Health Status among Men, funded by Merck Research Laboratories, and 168 black men participating in the Flint Men’s Health Study.  Researchers separated the participants into three categories based on differences between their baseline weight and weight during four year of follow-up: no weight loss, less than 5% of baseline weight loss, and more than 5% of baseline weight loss.

Jennifer L. St. Sauver, Ph.D., the lead author of the study, reported at the American Urological Association annual meeting that participants in both studies and in all weight categories experienced no statistically significant change in LUTS.  Her research team found that in the OCS cohort, weight loss was not related to receipt of treatment for benign prostatic hyperplasia.  Dr. St. Sauver concludes that although weight loss can help prevent a number of diseases such as diabetes, modest weight loss may not prevent development of LUTS.  A report of the study will be published in Urology. Data collection for this study was additionally funded by grants from the National Institutes of Health.

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